Structure, biophysics, and circuit function of a “giant” cortical presynaptic terminal

D Vandael, P Jonas - Science, 2024 - science.org
… Thus, the function of the hippocampal mossy fiber synapse may be more complex. … Electron
microscopy analysis revealed that large mossy fiber terminals form multiple active zones, …

[HTML][HTML] Three-dimensional structure of dendritic spines revealed by volume electron microscopy techniques

LK Parajuli, M Koike - Frontiers in Neuroanatomy, 2021 - frontiersin.org
… scanning electron microscopy; SBF-SEM, serial block-face scanning … of mossy fiber inputs
onto CA3 thorny excrescence spines, where multiple synaptic inputs (as many as 37 synaptic

Correlative light and volume electron microscopy to study brain development

S Hayashi, N Ohno, G Knott, Z Molnár - Microscopy, 2023 - academic.oup.com
… as well as in studying complex synaptic connections in thalamic … Serial block-face scanning
electron microscopy (SBF-SEM) [… multiple synapses with the connecting mossy fibre boutons […

Age-related changes in synaptic plasticity associated with mossy fiber terminal integration during adult neurogenesis

KD Murray, XB Liu, AN King, JD Luu, HJ Cheng - Eneuro, 2020 - eneuro.org
electron microscopy (EM), we describe the maturation of … We therefore focused these analyses
on the large complex … In addition, a recent serial block face EM reconstruction analysis in …

Maturation of complex synaptic connections of layer 5 cortical axons in the posterior thalamic nucleus requires SNAP25

S Hayashi, A Hoerder-Suabedissen… - Cerebral …, 2021 - academic.oup.com
… light and Serial block-face scanning electron microscopy (SBEM)… In mossy fiber boutons in
hippocampal CA3, synapses and … P7 and P14, which increases the complexity of the pre- and …

LRRTM3 regulates activity-dependent synchronization of synapse properties in topographically connected hippocampal neural circuits

J Kim, D Park, NY Seo, TH Yoon… - Proceedings of the …, 2022 - National Acad Sciences
… excitatory synaptic innervation of hippocampal mossy fibers (… ), serial block-face scanning
electron microscopy (SBF-SEM) … The complex structures of individual TEs are displayed by …

Uncovering brain tissue architecture across scales with super-resolution light microscopy

JM Michalska, J Lyudchik, P Velicky, H Korinkova… - bioRxiv, 2022 - biorxiv.org
… tailored analysis of putative synaptic cleft regions. Applying CATS to the hippocampal mossy
fiber … We analyzed complex mossy fiber boutons, but also smaller en passant boutons with …

… analysis of synapse morphology in an autism mouse model with 15q11-13 copy number variation using focused ion beam milling and scanning electron microscopy

Y Sato, S Okabe - Microscopy, 2019 - academic.oup.com
… knife (serial block face-scanning electron microscope; SBF-… Astrocytes form complex
morphology and a single cortical … Our previous study of spine-astrocytic contacts in hippocampal

[HTML][HTML] Imaging brain tissue architecture across millimeter to nanometer scales

JM Michalska, J Lyudchik, P Velicky… - Nature …, 2023 - nature.com
… mouse hippocampal mossy fiber circuitry, we reconstructed and quantified the synaptic input
… This highlights the complex organization of the mossy fiber circuitry, with signal integration …

[HTML][HTML] Targeted volumetric single-molecule localization microscopy of defined presynaptic structures in brain sections

M Pauli, MM Paul, S Proppert, A Mrestani… - Communications …, 2021 - nature.com
Serial sectioning 5 and serial block-face 6 scanning EM … , synaptic contacts formed by
hippocampal mossy fibers (MFs… The large size and highly complex geometry of MFBs with on …